Deepened sleep makes hippocampal spatial memory more persistent

Persistent modifications of hippocampal synaptic function during remote spatial memory.

A widely accepted notion for a process underlying memory formation is that learning changes the efficacy of synapses by the mechanism of synaptic plasticity. While there is compelling evidence of changes in synaptic efficacy observed after learning, demonstration of persistent synaptic changes accompanying memory has been elusive. We report that acquisition of a hippocampus and long-term potent...

Spatial memory and hippocampal enhancement

Given the central role of hippocampal function in spatial and episodic memory, the concept of enhancing it when compromised is attractive. This might be realised behaviourally, pharmacologically or via more radical routes such as brain stimulation. Successful approaches in each of these domains include trial-spacing, rest, and NMDA or cholinergic receptor modulation, but the goal of enhancement...

Nocturnal Mnemonics: Sleep and Hippocampal Memory Processing

As critical as waking brain function is to learning and memory, an established literature now describes an equally important yet complementary role for sleep in information processing. This overview examines the specific contribution of sleep to human hippocampal memory processing; both the detriments caused by a lack of sleep, and conversely, the proactive benefits that develop following the p...

Polymeric Gas Separation Membranes: What Makes them Industrially more Attractive?

Geometric Information Makes Spatial Query Processing More Efficient

More E cient Volker Gaede Institut f ur Wirtschaftsinformatik Humboldt-Universit at zu Berlin Spandauer Str. 1 10178 Berlin, Germany [email protected] Abstract In order to index complex and heterogeneous cartographic data by means of spatial access methods, one typically uses single, simple geometries to approximate the given geometries. Traditionally, no information regarding the quali...